I am an Associate Research Specialist at the Biodiversity Research Center, Academia Sinica (BRCAS), Taipei, Taiwan. I was a postdoctoral fellow at Genomic Research Center, Academia Sinica in 2005-2009. I obtained my PhD from the National Tsing-Hua University in 2004. I am equipped with molecular ecology and evolution, fish genomics and specialized in Nanopore sequencing. my current research topics focus on microbial application and evolution, phylogeography of freshwater fishes, fish genome evolution and interspecific mating behaviour. I have assisted BRC in (a) shared facility management and related training courses, (b) committees in AS bio-safety & BRC animal care experiments, and (c) new laboratory design and construction.
My major achievements involving research projects are

1. Natural selection on cis and trans regulation in yeasts
2. Cellulases identification by transcriptome and secretome analyses
3. Evolution of aerobic fermentation in yeasts
4. Opsin gene evolution in teleost
5. Biotransformation of triterpenoids by microbial enzymes
6. Fish genomes and interspecific mating behaviors

期刊論文

1. Goh KS, Lee CM, Wang TY*, 2022, “Species-Specific Flash Patterns Track the Nocturnal Behavior of Sympatric Taiwanese Fireflies”, Biology-Basel, 11(1), 58. (SCIE) (IF: 3.796; SCI ranking: 20.4%)
2. Wu JY, Ding HY, Wang TY, Tsai YL, Ting HJ, Chang TS*, 2021, “Improving Aqueous Solubility of Natural Antioxidant Mangiferin through Glycosylation by Maltogenic Amylase from Parageobacillus galactosidasius DSM 18751”, Antioxidants, 10(11), 1817. (SCIE) (IF: 5.014; SCI ranking: 11.5%,18.9%,7.2%)
3. Chiang CM, Wang TY, Wu JY, Zhang YR, Lin SY, Chang TS*, 2021, “Production of New Isoflavone Diglucosides from Glycosylation of 8-Hydroxydaidzein by Deinococcus geothermalis Amylosucrase”, Fermentation, 7(4), 232. (SCIE) (IF: 　; 　)
4. Wu JY, Wang TY, Ding HY, Zhang YR, Lin SY, Chang TS*, 2021, “Enzymatic Synthesis of Novel Vitexin Glucosides”, Molecules, 26, 6274. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
5. Gómez-Luciano LB, Wu YW, Chiang CM, Chang TS, Wu JY*, Wang TY*, 2021, “Complete Genome Sequence of the Soil-Isolated Psychrobacillus sp. Strain AK 1817, Capable of Biotransforming the Ergostane Triterpenoid Antcin K”, Microbiology Resource Announcements, 10(40), e01242-20. (SCIE) (IF: 　; 　)
6. Wu JY, Ding HY, Wang TY, Zhang YR, Chang TS*, 2021, “Glycosylation of Ganoderic Acid G by Bacillus Glycosyltransferases”, International Journal of Molecular Sciences, 22(18), 9744. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
7. Wang LJ, Wu YW, Wang TY*, 2021, “Characterization of the complete mitochondrial genome of Abscondita cerata (Olivier, 1911) (Coleoptera: Lampyridae) and its phylogenetic implications”, MITOCHONDRIAL DNA PART B-RESOURCES, 6(9), 2528-2530. (SCIE) (IF: 0.885; SCI ranking: 93.8%)
8. Chang TS*, Chiang CM, Wang TY, Tsai YL, Wu YW, Ting HJ*, Wu JY*, 2021, “One-Pot Bi-Enzymatic Cascade Synthesis of Novel Ganoderma Triterpenoid Saponins”, Catalysts, 11(5), 580. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
9. Chang TS, Wang TY, Chiang CM, Lin YJ, Chen HL, Wu YW, Ting HJ*, Wu JY, 2021, “Biotransformation of celastrol to a novel, well-soluble, low-toxic and anti-oxidative celastrol-29-O-β-glucoside by Bacillus glycosyltransferases”, Journal of Bioscience and Bioengineering, 131(2), 176-182. (SCIE) (IF: 2.366; SCI ranking: 54.5%,41.7%)
10. Liao NL, Huang SP, Wang TY*, 2020, “Interspecific mating behavior between introduced Zacco platypus and native Opsariichthys evolans in Taiwan”, Zoological Studies, 59, e6. (SCIE) (IF: 1.257; SCI ranking: 46.2%)
11. Mullis A, Lu Z, Zhan Y, Wang TY, Rodriguez J, Rajeh A, Chatrath A, Lin Z*, 2020, “Parallel concerted evolution of ribosomal protein genes in fungi and its adaptive significance”, Molecular Biology and Evolution, 37(2), 455-468. (SCIE) (IF: 11.062; SCI ranking: 6.1%,7.8%,3.9%)
12. Chang TS, Wang TY, Hsueh TY, Lee YW, Wu JY, Chiang CM, Chuang HM, Cai WX, Wu YW*, 2019, “A genome-centric approach reveals a novel glycosyltransferase from the GA A07 strain of Bacillus thuringiensis responsible for catalyzing 15-O-Glycosylation of ganoderic acid A”, International Journal of Molecular Sciences, 20(20), 5192. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
13. Chang TS, Chiang CM, Kao YH, Wu JY, Wu YW, Wang TY*, 2019, “A new triterpenoid glucoside from a novel acidic glycosylation of ganoderic acid A via recombinant glycosyltransferase of Bacillus subtilis”, Molecules, 24(19), 3457. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
14. Chang TS, Wang TY, Yang SY, Kao YH, Wu JY*, Chiang CM*, 2019, “Potential industrial production of a well-soluble, alkaline-stable, and anti-inflammatory isoflavone glucoside from 8-hydroxydaidzein glucosylated by recombinant amylosucrase of Deinococcus geothermalis”, Molecules, 24(12), 2236. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
15. Chang TS, Ko HH, Wang TY, Lee CH, Wu JY*, 2018, “Biotransformation of ganoderic acid A to 3-O-acetyl ganoderic acid A by soil-isolated Streptomyces sp.”, Fermentation, 4(4), 101.
16. Chang TS, Wu JY, Wang TY, Wu KY, Chiang CM*, 2018, “Uridine Diphosphate-Dependent Glycosyltransferases from Bacillus subtilis ATCC 6633 Catalyze the 15-O-Glycosylation of Ganoderic Acid A”, International Journal of Molecular Sciences, 19(11), 3469. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
17. Tseng WH, Lin JW, Lou CH, Lee KH, Wu LS, Wang TY, Wang FY*, Irschick DJ, Lin SM*, 2018, “Opsin gene expression regulated by testosterone level in a sexually dimorphic lizard”, Scientific Reports, 8, 16055. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
18. Chang TS, Chiang CM, Wang TY, Lee CH, Lee YW, Wu JY*, 2018, “New triterpenoid from novel triterpenoid 15-O-glycosylation on ganoderic acid A by intestinal bacteria of zebrafish”, Molecules, 23(9), 2345. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
19. Chiang CM, Wang TY, Yang SY, Wu JY*, Chang TS*, 2018, “Production of new isoflavone glucosides from glycosylation of 8-hydroxydaidzein by glycosyltransferase from Bacillus subtilis ATCC 6633”, Catalysts, 8(9), 387. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
20. Lee MH, Lin JJ, Lin YJ, Chang JJ, Ke HM, Fan WL, Wang TY, Li WH*, 2018, “Genome-wide prediction of CRISPR/Cas9 targets in Kluyveromyces marxianus and its application to obtain a stable haploid strain”, Scientific Reports, 8(1), 7305. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
21. Huang SP, Wang FY, Wang TY*, 2017, “Molecular phylogeny of the Opsariichthys group (Teleostei: Cypriniformes) based on complete mitochondrial genomes”, Zoological Studies, 56, 40. (SCIE) (IF: 1.257; SCI ranking: 46.2%)
22. Lin JJ, Wang FY, Li WH*, Wang TY*, 2017, “The rises and falls of opsin genes in 59 ray-finned fish genomes and their implications for environmental adaptation”, Scientific Reports, 7(1), 15568. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
23. Chiang CM, Wang TY, Ke AN, Chang TS*, Wu JY*, 2017, “Biotransformation of ergostane triterpenoid antcin K from Antrodia cinnamomea by soil-isolated Psychrobacillus sp. AK 1817”, Catalysts, 7(10), 299. (SCIE) (IF: 3.52; SCI ranking: 40.9%)

專書、論文集

專書(論文集)之一章

學術會議(研討會)論文